Drug-Like Properties, Second Edition: Concepts, Structure Design and Methods from ADME to Toxicity Optimization
| Author | : | |
| Rating | : | 4.54 (622 Votes) |
| Asin | : | 0128010762 |
| Format Type | : | paperback |
| Number of Pages | : | 580 Pages |
| Publish Date | : | 2013-12-25 |
| Language | : | English |
DESCRIPTION:
About the Author Li Di is an Associate Research Fellow at Pfizer, USA
This valuable resource explores physiochemical properties, including solubility and permeability, before exploring how compounds are absorbed, distributed, and metabolized safely and stably. Through valuable case studies, structure-property relationship descriptions, and structure modification strategies, Drug-Like Properties, Second Edition, offers tools and methods for ADME/Tox scientists through all aspects of drug research, discovery, design, development, and optimization.Provides a comprehensive and valuable working handbook for scientists and students in medicinal chemistryIncludes expanded coverage of pharmacokinetics fundamentals and effectsContains updates throughout, including the authors’ rece
Li Di is an Associate Research Fellow at Pfizer, USA